Genetics

A new study from researchers in Serbia uncovers how small genetic differences in iron-regulating and cell-death–related genes may influence how aggressively multiple sclerosis (MS) progresses. By examining variants in genes like MAP1B, CDKN1A, and EGLN2, the team found sex-specific links between these genes, iron metabolism, and neurodegeneration—suggesting that MS severity isn’t just about immune dysfunction, but also how our cells handle stress, oxygen, and iron. This research opens the door to more personalized approaches to understanding and treating MS.