Genetics
Multiple Sclerosis, Dimethyl Fumarate, and Genetic Variation01, May 2025
Alper Bülbül
01, May 2025
This blog post explores the complex relationship between multiple sclerosis (MS), a debilitating autoimmune disease, and dimethyl fumarate (DMF), a widely used oral treatment. It breaks down how DMF works to protect the nervous system, summarizes its clinical benefits, and addresses potential side effects like lymphopenia. What makes this discussion especially timely is the focus on how individual genetic differences—such as variations in the NOX3 gene and specific immune-related gene expression profiles—can influence how well patients respond to DMF. By highlighting emerging research in pharmacogenomics, the post emphasizes the promise of personalized medicine in making MS treatment more effective and safer for each patient.
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