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Uncovering the Proteins Behind Multiple Sclerosis: How a Multi-Omics Breakthrough Reveals New Clues in the Blood and Brain
Uncovering the Proteins Behind Multiple Sclerosis: How a Multi-Omics Breakthrough Reveals New Clues in the Blood and Brain

This blog post explores a groundbreaking multi-omics study that identified 39 previously unknown plasma and brain proteins linked to multiple sclerosis risk and progression. By integrating genetics, proteomics, bulk tissue transcriptomics, and single-cell data—and validating findings in a long-term clinical cohort—the research uncovers how specific immune and brain cell types may drive MS biology. The post translates these complex findings into a clear, humanized narrative that highlights new biomarker candidates, potential therapeutic targets, and fresh insights into how MS begins and advances.

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